This work discusses the use of words and expressions of the Bible found with offensive value in contexts of verbal interaction between Portuguese speakers, especially the group of evangelicals, who create and use a good part of this lexicon in their linguistic routines- interactional. In order to understand how the lexicon of offense acts in these interactions, theoretical aspects associated with linguistic, pragmatic, cultural and intercultural aspects are used, through authors such as Hall (1976), Brown and Levinson (1987), Culpeper (1996; 2010), DaMatta (1997), Hofstede (2001) and Carretero (2011). The results of the analysis of twenty-one expressions collected on the social network Twitter demonstrate that its use is quite productive, by enabling the act of offending someone without the use of usual offenses and profanity, replacing them with biblical expressions. According to the six categories of analysis adopted, different types of offenses and their respective contexts of use are identified. This research contributes to the areas of religious studies and Portuguese as a Second/Foreign Language (PSL/PFL); for the latter, three proposals for didactic application are presented.