This study aims to analyze different methods to predict the fatigue life in pipelines with dents loaded with internal pressure. A new method is proposed which makes previsions based on the SN method; the mean pressure is taken into account according to the parabola of Gerber. Some other methods available in the literature are analyzed in terms of their safety factors and experimental validation. The stress analysis has been performed for the different methods using Abaqus 6.10, a Finite Element analysis software, except in those cases where a regression curve, based on numerical results, are provided. All the results found have been compared against experimental results available in the literature. A total of eight methods have been evaluated in six cases with different linepipe wall thicknesses, indentor diameters, materials and initial pressures. The results indicate that that different methods produce different life predictions, and the new method presented predict lives with a good match to the experimental data without using safety or reliability factors.